ALSBERG LAB RESEARCH
ALSBERG LAB RESEARCH
Our laboratory focuses on engineering functional biologic replacements to repair damaged or diseased tissues in the body. We use the complex signals that are implicated in tissue morphogenesis, repair, and homeostasis as a template for the development of innovative biomaterials for tissue regeneration. Through the precise temporal and spatial presentation of soluble bioactive factors, mechanical forces, and biomaterial physical and biochemical properties, we aspire to create microenvironments that regulate cell gene expression and new tissue formation.
Some areas of active investigation include innovative biomaterials, microenvironments and bioactive factor delivery vehicles for functional tissue engineering, regenerative medicine and disease therapeutics; developmental engineering; control of stem cell fate decision; precise temporal and spatial presentation of signals to regulate cell function; 4D systems; biofabrication and bioprinting; mechanotransduction and the influence of mechanics on cell behavior and tissue formation; organoids and organogenesis; therapeutic angiogenesis; and cell-cell interactions.
Some areas of active investigation include innovative biomaterials, microenvironments and bioactive factor delivery vehicles for functional tissue engineering, regenerative medicine and disease therapeutics; developmental engineering; control of stem cell fate decision; precise temporal and spatial presentation of signals to regulate cell function; 4D systems; biofabrication and bioprinting; mechanotransduction and the influence of mechanics on cell behavior and tissue formation; organoids and organogenesis; therapeutic angiogenesis; and cell-cell interactions.